UW Virology Research Clinic

July 12, 2021

“Mix ‘n Match” Booster COVID-19 Vaccine Clinical Trial

Updated 03/14/2022

Adults Needed for UW COVID-19 Vaccine Booster Clinical Trial

The University of Washington is seeking volunteers for a Phase 1/2 COVID-19 vaccine booster trial.  The purpose of this clinical trial is to test the safety and effectiveness of a booster dose of the Novavax sub-unit protein vaccine in people who have received an EUA vaccine series.

The study will enroll:

  • Participants who have completed an EUA vaccine series at least 12 weeks prior to joining the study.
  • This includes individuals who have received either 2 doses of Pfizer OR 2 doses of Moderna OR 2 doses of Johnson & Johnson COVID-19 vaccines. You will not be eligible if you have received a 3rd (booster) COVID-19 vaccine.

The trial will last for about one year and will involve at least 7 in-person visits.

Participants will undergo a screening assessment to see whether they are eligible. Study visits will involve physical exams, blood draws, and vaccine injections.  Participants will be asked to keep a diary of their vaccine reactions for 7 days after each injection. 

To be eligible for the trial you must:

  • Be 18 years of age or older
  • Have received an EUA vaccine no less than 12 weeks ago

Conditions which would prevent you from participating:

  • Previous SARS-CoV-2 infection
  • Current pregnancy or breastfeeding
  • Serious reactions to vaccines
  • Immunocompromising conditions


For completing the entire study, participants will be compensated $800.

Clinic Location: Our clinic is located on the 11th floor of the Ninth and Jefferson Building at Harborview Medical Center. We are open Monday through Friday 8:30am to 5:30pm.

Please contact us at 206-520-4212 or email us at vteu@uw.edu for more information. You can also find more information on the NIH’s webpage for this clinical trial.